piRNA piRNA全名Piwi-interacting RNA,是一類小型RNA分子,長度大約是29到30個核苷酸。只表現(xiàn)在哺乳動物的睪丸中,并且可以和Piwi蛋白結合形成piRNA復合物(piRNA complexes,piRCs)。與RNA沉默(RNA silencing)作用有關。
相關文獻
- N.C. Lau et al., "Characterization of the piRNA Complex from Rat Testes," Science 313, 363 (2006)
- V.N. Kim, "Small RNAs Just Got Bigger: Piwi-Interacting RNAs (piRNAs) in Mammalian Testes," Genes Dev. 20, 1993 (2006)
- A. Girard et al., "A Germline-Specific Class of Small RNAs Binds Mammalian Piwi Proteins," Nature 442, 199 (2006)
- A. Aravin et al., "A Novel Class of Small RNAs Bind to MILI Protein in Mouse Testes," Nature 442, 203 (2006)
- S.T. Grivna et al., "A Novel Class of Small RNAs in Mouse Spermatogenic Cells," Genes Dev. 20, 1709 (2006)
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